INTRODUCTION. During eukaryotic translation initiation, 80S ribosomes are assembled on the messenger RNA. This process is highly regulated and can be divided into several phases: a ternary complex (TC) - consisting of trimeric eukaryotic initiation factor 2 (eIF2), GTP and initiator methionyl-tRNA (Met-tRNAi) - binds to the small ribosomal …
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